Seminars in Roentgenology
Volume 43, Issue 3 , Pages 183-192 , July 2008

Cardiac Magnetic Resonance Imaging for the Evaluation of Ventricular Function

  • Ammar Sarwar, MD

      Affiliations

    • Drs. Sarwar and Shapiro contributed equally to the preparation of this article.
    • ,
  • Michael D. Shapiro, DO

      Affiliations

    • Drs. Sarwar and Shapiro contributed equally to the preparation of this article.
    • ,
  • Suhny Abbara, MD
    • ,
  • Ricardo C. Cury, MD

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Ricardo C. Cury, MD, Massachusetts General Hospital and Harvard Medical School, 165 Cambridge Street Suite 400; Boston, MA 02114.

References 

  1. Pattynama PM, Lamb HJ, van der Velde EA, et al. Left ventricular measurements with cine and spin-echo MR imaging: a study of reproducibility with variance component analysis. Radiology. 1993;187:261–268
  2. Grothues F, Moon JC, Bellenger NG, et al. Interstudy reproducibility of right ventricular volumes, function, and mass with cardiovascular magnetic resonance. Am Heart J. 2004;147:218–223
  3. Sechtem U, Pflugfelder PW, Gould RG, et al. Measurement of right and left ventricular volumes in healthy individuals with cine MR imaging. Radiology. 1987;163:697–702
  4. Lorenz CH, Walker ES, Morgan VL, et al. Normal human right and left ventricular mass, systolic function, and gender differences by cine magnetic resonance imaging. J Cardiovasc Magn Reson. 1999;1:7–21
  5. Longmore DB, Klipstein RH, Underwood SR, et al. Dimensional accuracy of magnetic resonance in studies of the heart. Lancet. 1985;1:1360–1362
  6. Rehr RB, Malloy CR, Filipchuk NG, et al. Left ventricular volumes measured by MR imaging. Radiology. 1985;156:717–719
  7. Helbing WA, Rebergen SA, Maliepaard C, et al. Quantification of right ventricular function with magnetic resonance imaging in children with normal hearts and with congenital heart disease. Am Heart J. 1995;130:828–837
  8. Pattynama PM, Doornbos J, Hermans J, et al. Magnetic resonance evaluation of regional left ventricular function (Effect of through-plane motion). Invest Radiol. 1992;27:681–685
  9. Utz JA, Herfkens RJ, Heinsimer JA, et al. Cine MR determination of left ventricular ejection fraction. AJR Am J Roentgenol. 1987;148:839–843
  10. Barkhausen J, Ruehm SG, Goyen M, et al. MR evaluation of ventricular function: true fast imaging with steady-state precession versus fast low-angle shot cine MR imaging: feasibility study. Radiology. 2001;219:264–269
  11. Carr JC, Simonetti O, Bundy J, et al. Cine MR angiography of the heart with segmented true fast imaging with steady-state precession. Radiology. 2001;219:828–834
  12. Bloomgarden DC, Fayad ZA, Ferrari VA, et al. Global cardiac function using fast breath-hold MRI: validation of new acquisition and analysis techniques. Magn Reson Med. 1997;37:683–692
  13. Chia JM, Fischer SE, Wickline SA, et al. Performance of QRS detection for cardiac magnetic resonance imaging with a novel vectorcardiographic triggering method. J Magn Reson Imaging. 2000;12:678–688
  14. Bellenger NG, Gatehouse PD, Rajappan K, et al. Left ventricular quantification in heart failure by cardiovascular MR using prospective respiratory navigator gating: comparison with breath-hold acquisition. J Magn Reson Imaging. 2000;11:411–417
  15. Hori Y, Yamada N, Higashi M, et al. Rapid evaluation of right and left ventricular function and mass using real-time true-FISP cine MR imaging without breath-hold: comparison with segmented true-FISP cine MR imaging with breath-hold. J Cardiovasc Magn Reson. 2003;5:439–450
  16. Alfakih K, Reid S, Jones T, et al. Assessment of ventricular function and mass by cardiac magnetic resonance imaging. Eur Radiol. 2004;14:1813–1822
  17. Levy D, Garrison RJ, Savage DD, et al. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med. 1990;322:1561–1566
  18. Cranney GB, Lotan CS, Dean L, et al. Left ventricular volume measurement using cardiac axis nuclear magnetic resonance imaging (Validation by calibrated ventricular angiography). Circulation. 1990;82:154–163
  19. Chuang ML, Beaudin RA, Riley MF, et al. Three-dimensional echocardiographic measurement of left ventricular mass: comparison with magnetic resonance imaging and two-dimensional echocardiographic determinations in man. Int J Card Imaging. 2000;16:347–357
  20. Maddahi J, Crues J, Berman DS, et al. Noninvasive quantification of left ventricular myocardial mass by gated proton nuclear magnetic resonance imaging. J Am Coll Cardiol. 1987;10:682–692
  21. Pennell DJ. Ventricular volume and mass by CMR. J Cardiovasc Magn Reson. 2002;4:507–513
  22. Kozerke S, Scheidegger MB, Pedersen EM, et al. Heart motion adapted cine phase-contrast flow measurements through the aortic valve. Magn Reson Med. 1999;42:970–978
  23. Cerqueira MD, Weissman NJ, Dilsizian V, et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation. 2002;105:539–542
  24. Galasko GI, Basu S, Lahiri A, et al. A prospective comparison of echocardiographic wall motion score index and radionuclide ejection fraction in predicting outcome following acute myocardial infarction. Heart. 2001;86:271–276
  25. Sheehan FH, Bolson EL, Dodge HT, et al. Advantages and applications of the centerline method for characterizing regional ventricular function. Circulation. 1986;74:293–305
  26. Buller VG, van der Geest RJ, Kool MD, et al. Assessment of regional left ventricular wall parameters from short axis magnetic resonance imaging using a three-dimensional extension to the improved centerline method. Invest Radiol. 1997;32:529–539
  27. Mogelvang J, Stubgaard M, Thomsen C, et al. Evaluation of right ventricular volumes measured by magnetic resonance imaging. Eur Heart J. 1988;9:529–533
  28. Mackey ES, Sandler MP, Campbell RM, et al. Right ventricular myocardial mass quantification with magnetic resonance imaging. Am J Cardiol. 1990;65:529–532
  29. Pattynama PM, Lamb HJ, Van der Velde EA, et al. Reproducibility of MRI-derived measurements of right ventricular volumes and myocardial mass. Magn Reson Imaging. 1995;13:53–63
  30. Blake LM, Scheinman MM, Higgins CB. MR features of arrhythmogenic right ventricular dysplasia. AJR Am J Roentgenol. 1994;162:809–812
  31. Vonk-Noordegraaf A, Marcus JT, Holverda S, et al. Early changes of cardiac structure and function in COPD patients with mild hypoxemia. Chest. 2005;127:1898–1903
  32. Weber OM, Higgins CB. MR evaluation of cardiovascular physiology in congenital heart disease: flow and function. J Cardiovasc Magn Reson. 2006;8:607–617
  33. Markiewicz W, Sechtem U, Higgins CB. Evaluation of the right ventricle by magnetic resonance imaging. Am Heart J. 1987;113:8–15
  34. Gopal AS, Chukwu EO, Iwuchukwu CJ, et al. Normal values of right ventricular size and function by real-time 3-dimensional echocardiography: comparison with cardiac magnetic resonance imaging. J Am Soc Echocardiogr. 2007;20:445–455
  35. Jauhiainen T, Jarvinen VM, Hekali PE. Evaluation of methods for MR imaging of human right ventricular heart volumes and mass. Acta Radiol. 2002;43:587–592
  36. Zerhouni EA, Parish DM, Rogers WJ, et al. Human heart: tagging with MR imaging—a method for noninvasive assessment of myocardial motion. Radiology. 1988;169:59–63
  37. Axel L, Dougherty L. Heart wall motion: improved method of spatial modulation of magnetization for MR imaging. Radiology. 1989;172:349–350
  38. Fischer SE, McKinnon GC, Maier SE, et al. Improved myocardial tagging contrast. Magn Reson Med. 1993;30:191–200
  39. Axel L, Montillo A, Kim D. Tagged magnetic resonance imaging of the heart: a survey. Med Image Anal. 2005;9:376–393
  40. MacGowan GA, Shapiro EP, Azhari H, et al. Noninvasive measurement of shortening in the fiber and cross-fiber directions in the normal human left ventricle and in idiopathic dilated cardiomyopathy. Circulation. 1997;96:535–541
  41. Rademakers FE, Rogers WJ, Guier WH, et al. Relation of regional cross-fiber shortening to wall thickening in the intact heart (Three-dimensional strain analysis by NMR tagging). Circulation. 1994;89:1174–1182
  42. Moore CC, O'Dell WG, McVeigh ER, et al. Calculation of three-dimensional left ventricular strains from biplanar tagged MR images. J Magn Reson Imaging. 1992;2:165–175
  43. Croisille P, Moore CC, Judd RM, et al. Differentiation of viable and nonviable myocardium by the use of three-dimensional tagged MRI in 2-day-old reperfused canine infarcts. Circulation. 1999;99:284–291
  44. Rosen BD, Gerber BL, Edvardsen T, et al. Late systolic onset of regional LV relaxation demonstrated in three-dimensional space by MRI tissue tagging. Am J Physiol Heart Circ Physiol. 2004;287:H1740–H1746
  45. Edvardsen T, Rosen BD, Pan L, et al. Regional diastolic dysfunction in individuals with left ventricular hypertrophy measured by tagged magnetic resonance imaging–the Multi-Ethnic Study of Atherosclerosis (MESA). Am Heart J. 2006;151:109–114
  46. Dong SJ, Hees PS, Huang WM, et al. Independent effects of preload, afterload, and contractility on left ventricular torsion. Am J Physiol. 1999;277:H1053–H1060
  47. Zwanenburg JJ, Gotte MJ, Kuijer JP, et al. Timing of cardiac contraction in humans mapped by high-temporal-resolution MRI tagging: early onset and late peak of shortening in lateral wall. Am J Physiol Heart Circ Physiol. 2004;286:H1872–H1880
  48. Fonseca CG, Oxenham HC, Cowan BR, et al. Aging alters patterns of regional nonuniformity in LV strain relaxation: a 3-D MR tissue tagging study. Am J Physiol Heart Circ Physiol. 2003;285:H621–H630
  49. Oxenham HC, Young AA, Cowan BR, et al. Age-related changes in myocardial relaxation using three-dimensional tagged magnetic resonance imaging. J Cardiovasc Magn Reson. 2003;5:421–430
  50. Vasan RS, Benjamin EJ. Diastolic heart failure—no time to relax. N Engl J Med. 2001;344:56–59
  51. Redfield MM, Jacobsen SJ, Burnett JC, et al. Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic. JAMA. 2003;289:194–202
  52. Grossman W. Defining diastolic dysfunction. Circulation. 2000;101:2020–2021
  53. Suzuki J, Caputo GR, Masui T, et al. Assessment of right ventricular diastolic and systolic function in patients with dilated cardiomyopathy using cine magnetic resonance imaging. Am Heart J. 1991;122:1035–1040
  54. Fujita N, Hartiala J, O'Sullivan M, et al. Assessment of left ventricular diastolic function in dilated cardiomyopathy with cine magnetic resonance imaging: effect of an angiotensin converting enzyme inhibitor, benazepril. Am Heart J. 1993;125:171–178
  55. Lamb HJ, Singleton RR, van der Geest RJ, et al. MR imaging of regional cardiac function: low-pass filtering of wall thickness curves. Magn Reson Med. 1995;34:498–502
  56. Hartiala JJ, Mostbeck GH, Foster E, et al. Velocity-encoded cine MRI in the evaluation of left ventricular diastolic function: measurement of mitral valve and pulmonary vein flow velocities and flow volume across the mitral valve. Am Heart J. 1993;125:1054–1066
  57. Kayser HW, Stoel BC, van der Wall EE, et al. MR velocity mapping of tricuspid flow: correction for through-plane motion. J Magn Reson Imaging. 1997;7:669–673
  58. Mohiaddin RH, Gatehouse PD, Henien M, et al. Cine MR Fourier velocimetry of blood flow through cardiac valves: comparison with Doppler echocardiography. J Magn Reson Imaging. 1997;7:657–663
  59. Garot J, Bluemke DA, Osman NF, et al. Fast determination of regional myocardial strain fields from tagged cardiac images using harmonic phase MRI. Circulation. 2000;101:981–988
  60. Yamanari H, Kakishita M, Fujimoto Y, et al. Effect of regional myocardial perfusion abnormalities on regional myocardial early diastolic function in patients with hypertrophic cardiomyopathy. Heart Vessels. 1997;12:192–198
  61. Mandinov L, Eberli FR, Seiler C, et al. Diastolic heart failure. Cardiovasc Res. 2000;45:813–825
  62. Hartiala JJ, Foster E, Fujita N, et al. Evaluation of left atrial contribution to left ventricular filling in aortic stenosis by velocity-encoded cine MRI. Am Heart J. 1994;127:593–600
  63. Nagel E, Stuber M, Burkhard B, et al. Cardiac rotation and relaxation in patients with aortic valve stenosis. Eur Heart J. 2000;21:582–589
  64. Singh GK, Greenberg SB, Yap YS, et al. Right ventricular function and exercise performance late after primary repair of tetralogy of Fallot with the transannular patch in infancy. Am J Cardiol. 1998;81:1378–1382
  65. Florentine MS, Grosskreutz CL, Chang W, et al. Measurement of left ventricular mass in vivo using gated nuclear magnetic resonance imaging. J Am Coll Cardiol. 1986;8:107–112
  66. Germain P, Roul G, Kastler B, et al. Inter-study variability in left ventricular mass measurement (Comparison between M-mode echography and MRI). Eur Heart J. 1992;13:1011–1019
  67. Myerson SG, Montgomery HE, World MJ, et al. Left ventricular mass: reliability of M-mode and 2-dimensional echocardiographic formulas. Hypertension. 2002;40:673–678
  68. Allison JD, Flickinger FW, Wright JC, et al. Measurement of left ventricular mass in hypertrophic cardiomyopathy using MRI: comparison with echocardiography. Magn Reson Imaging. 1993;11:329–334
  69. Bellenger NG, Burgess MI, Ray SG, et al. Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance; are they interchangeable?. Eur Heart J. 2000;21:1387–1396
  70. Mascarenhas NB, Muthupillai R, Cheong B, et al. Fast 3D cine steady-state free precession imaging with sensitivity encoding for assessment of left ventricular function in a single breath-hold. AJR Am J Roentgenol. 2006;187:1235–1239
  71. Maceira AM, Prasad SK, Khan M, et al. Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2006;8:417–426
  72. Maceira AM, Prasad SK, Khan M, et al. Reference right ventricular systolic and diastolic function normalized to age, gender and body surface area from steady-state free precession cardiovascular magnetic resonance. Eur Heart J. 2006;27:2879–2888

PII: S0037-198X(08)00026-6

doi: 10.1053/j.ro.2008.02.004

Seminars in Roentgenology
Volume 43, Issue 3 , Pages 183-192 , July 2008

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