Seminars in Roentgenology
Volume 43, Issue 1 , Pages 50-59 , January 2008

Imaging Pediatric Abdominal Tumors

  • Sue C. Kaste, DO

      Affiliations

    • Department of Radiological Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee.
    • Department of Oncology, St. Jude Children’s Research Hospital, Memphis, Tennessee.
    • Department of Radiology, University of Tennessee Health Science Center, Memphis, Tennessee.
    • Corresponding Author InformationAddress reprint requests to Sue C. Kaste, DO, Division of Diagnostic Imaging, Department of Radiological Sciences, St. Jude Children’s Research Hospital, 332 N. Lauderdale, Memphis, TN 38105-2794.
    • ,
  • M. Beth McCarville, MD

      Affiliations

    • Department of Radiological Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee.

References 

  1. Gow KW, Lensing S, Hill DA, et al. Thyroid carcinoma presenting in childhood or after treatment of childhood malignancies: An institutional experience and review of the literature. J Pediatr Surg. 2003;38:1574–1580
  2. Broudeur GM, Maris JM. Neuroblastoma. In:  Pizzo PA editors. Principles and Practice of Pediatric Oncology. (ed 5). Philadelphia, PA: Lippincott Williams & Wilkins; 2006;p. 933–970PDG
  3. Rha SE, Byun JY, Jung SE, et al. Neurogenic tumors in the abdomen: tumor types and imaging characteristics. Radiographics. 2003;23:29–43
  4. Shimada H, Umehara S, Monobe Y, et al. International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors: a report from the Children’s Cancer Group. Cancer. 2001;92:2451–2461
  5. Maris JM. The biologic basis for neuroblastoma heterogeneity and risk stratification. Curr Opin Pediatr. 2005;17:7–13
  6. Papaioannou G, McHugh K. Neuroblastoma in childhood: review and radiological findings. Cancer Imaging. 2005;5:116–127
  7. Hugosson C, Nyman R, Jorulf H, et al. Imaging of abdominal neuroblastoma in children. Acta Radiol. 1999;40:534–542
  8. In:  Pizzo PA,  Poplack DG editor. Renal tumors, in Principles and Practice of Pediatric Oncology. (ed 5). Philadelphia, PA: Lippincott Williams & Wilkins; 2007;
  9. Hiorns MP, Owens CM. Radiology of neuroblastoma in children. Eur Radiol. 2001;11:2071–2081
  10. Kushner BH. Neuroblastoma: a disease requiring a multitude of imaging studies. J Nucl Med. 2004;45:1172–1188
  11. Lonergan GJ, Schwab CM, Suarez ES, et al. Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: radiologic-pathologic correlation. Radiographics. 2002;22:911–934
  12. Goo HW, Choi SH, Ghim T, et al. Whole-body MRI of paediatric malignant tumours: comparison with conventional oncological imaging methods. Pediatr Radiol. 2005;35:766–773
  13. Laffan EE, O’Connor R, Ryan SP, et al. Whole-body magnetic resonance imaging: a useful additional sequence in paediatric imaging. Pediatr Radiol. 2004;34:472–480
  14. Meyer JS, Siegel MJ, Farooqui SO, et al. Which MRI sequence of the spine best reveals bone-marrow metastases of neuroblastoma?. Pediatr Radiol. 2005;35:778–785
  15. Siegel MJ, Ishwaran H, Fletcher BD, et al. Staging of neuroblastoma at imaging: report of the radiology diagnostic oncology group. Radiology. 2002;223:168–175
  16. Raney RB, Tefft M, Maurer HM, et al. Disease patterns and survival rate in children with metastatic soft-tissue sarcoma (A report from the Intergroup Rhabdomyosarcoma Study (IRS)-I). Cancer. 1988;62:1257–1266
  17. Pappo AS, Shapiro DN, Crist WM, et al. Biology and therapy of pediatric rhabdomyosarcoma. J Clin Oncol. 1995;13:2123–2139
  18. Lawrence W, Anderson JR, Gehan EA, et al. Children’s Cancer Study Group Pretreatment TNM staging of childhood rhabdomyosarcoma: a report of the Intergroup Rhabdomyosarcoma Study Group. Pediatr Oncol Group Cancer. 1997;80:1165–1170
  19. Kaefer M, Rink RC. Genitourinary rhabdomyosarcoma (Treatment options). Urol Clin North Am. 2000;27:471–487
  20. Donnelly LF, Bisset GS, Frush DP. Diagnosis please (Case 2: embryonal rhabdomyosarcoma of the biliary tree). Radiology. 1998;208:621–623
  21. Roebuck DJ, Yang WT, Lam WW, et al. Hepatobiliary rhabdomyosarcoma in children: diagnostic radiology. Pediatr Radiol. 1998;28:101–108
  22. Tannous WN, Azouz EM, Homsy YL, et al. CT and ultrasound imaging of pelvic rhabdomyosarcoma in children (A review of 56 patients). Pediatr Radiol. 1989;19:530–534
  23. Roebuck DJ, Yang WT, Lam WW, et al. Hepatobiliary rhabdomyosarcoma in children: diagnostic radiology. Pediatr Radiol. 1998;28:101–108
  24. Lang P, Johnston JO, Arenal-Romero F, et al. Advances in MR imaging of pediatric musculoskeletal neoplasms. Magn Reson Imaging Clin North Am. 1998;6:579–604
  25. Meyer JS, Dormans JP. Differential diagnosis of pediatric musculoskeletal masses. Magn Reson Imaging Clin North Am. 1998;6:561–577
  26. Enzinger FM, Weiss SW. Soft tissue tumors. In:  Enzinger FM editors. Rhabdomyosarcoma. (ed 3). 1995;p. 539–577St. Louis, MO
  27. Crist W, Gehan EA, Ragab AH, et al. The Third Intergroup Rhabdomyosarcoma Study. J Clin Oncol. 1995;13:610–630
  28. Vade A, Blane CE. Imaging of Burkitt lymphoma in pediatric patients. Pediatr Radiol. 1985;15:123–126
  29. Arber DA, Downing JR, Cleary ML. Pathology and molecular diagnosis of leukemias and lymphomas. In:  Pizzo PA,  Poplack DG editor. Principles and Practice of Pediatric Oncology. (ed 5). Philadelphia, PA: Lippincott Williams & Wilkins; 2006;p. 160–184
  30. Krudy AG, Dunnick NR, Magrath IT, et al. CT of American Burkitt lymphoma. AJR Am J Roentgenol. 1981;136:747–754
  31. Miller JH, Hindman BW, Lam AH. Ultrasound in the evaluation of small bowel lymphoma in children. Radiology. 1980;135:409–414
  32. Link MP, Weinstein HJ. Malignant non-Hodgkin lymphomas in children. In:  Pizzo PA,  Poplack DG editor. Principles and Practice of Pediatric Oncology. (ed 5). Philadelphia, PA: Lippincott Williams & Wilkins; 2006;p. 722–747
  33. Jung C, Choi YY, Cho S, et al. Symptomatic cortical desmoids detected on knee SPECT. Clin Nucl Med. 2002;27:437–438
  34. Paling MR, Williamson BR. Adrenal involvement in non-Hodgkin lymphoma. AJR Am J Roentgenol. 1983;141:303–305
  35. Pickhardt PJ, Siegel MJ, Hayashi RJ, et al. Posttransplantation lymphoproliferative disorder in children: clinical, histopathologic, and imaging features. Radiology. 2000;217:16–25
  36. Petit P, Panuel M, Scheiner C, et al. Calcifications in untreated primary duodenal lymphoma: an exceptional entity. Pediatr Radiol. 1994;24:283–284
  37. Laufer L, Barki Y, Schulman H, et al. Calcification in an untreated case of Burkitt’s lymphoma: radiographic, ultrasound and CT diagnosis. Pediatr Radiol. 1994;24:180–181
  38. Glass RB, Fernbach SK, Conway JJ, et al. Gallium scintigraphy in American Burkitt lymphoma: accurate assessment of tumor load and prognosis. AJR Am J Roentgenol. 1985;145:671–676
  39. Shirkhoda A, Staab EV, Mittelstaedt CA. Renal lymphoma imaged by ultrasound and gallium-67. Radiology. 1980;137:175–180
  40. Graif M, Kessler A, Neumann Y, et al. Pancreatic Burkitt lymphoma in AIDS: sonographic appearance. AJR Am J Roentgenol. 1987;149:1290–1291
  41. Bar-Shalom R, Yefremov N, Haim N, et al. Camera-based FDG PET and 67Ga SPECT in evaluation of lymphoma: comparative study. Radiology. 2003;227:353–360
  42. Sasaki M, Kuwabara Y, Koga H, et al. Clinical impact of whole body FDG-PET on the staging and therapeutic decision making for malignant lymphoma. Ann Nucl Med. 2002;16:337–345
  43. Wirth A, Seymour JF, Hicks RJ, et al. Fluorine-18 fluorodeoxyglucose positron emission tomography, gallium-67 scintigraphy, and conventional staging for Hodgkin’s disease and non-Hodgkin’s lymphoma. Am J Med. 2002;112:262–268
  44. Jhanwar YS, Straus DJ. The role of PET in lymphoma. J Nucl Med. 2006;47:1326–1334
  45. Kaste SC, Shulkin BL. 18F-fluorodeoxyglucose PET/CT in childhood lymphoma. In:  Israel O editors. PET Clinics Lymphoma. vol. 1:2006;p. 265–273Philadelphia, PA
  46. Spaepen K, Stroobants S, Dupont P, et al. [(18)F]FDG PET monitoring of tumour response to chemotherapy: does [(18)F]FDG uptake correlate with the viable tumour cell fraction?. Eur J Nucl Med Mol Imaging. 2003;30:682–688
  47. Okada J, Yoshikawa K, Imazeki K, et al. The use of FDG-PET in the detection and management of malignant lymphoma: correlation of uptake with prognosis. J Nucl Med. 1991;32:686–691
  48. Ojha B, Bender LW, Francisco R, et al. Recurrent lymphoma detected on F-18 FDG coincidence imaging with negative findings on Ga-67 citrate scintigraphy. Clin Nucl Med. 2002;27:638–640
  49. Ries LAG, Eisner MP, Kosary CL, et al. SEER Cancer Statistics Review, 1975-2000. Bethesda, MD: National Cancer Institute; 2003;
  50. Ehrlich PF. Wilms tumor: progress to date and future considerations. Exp Rev Anticancer Ther. 2001;1:555–564
  51. Wilimas JA, Kaste SC, Kauffman WM, et al. Use of chest computed tomography in the staging of pediatric Wilms’ tumor: interobserver variability and prognostic significance. J Clin Oncol. 1997;15:2631–2635
  52. Dome JS, Coppes MJ. Recent advances in Wilms tumor genetics. Curr Opin Pediatr. 2002;14:5–11
  53. Dome JS, Perlman EJ, Ritchey ML, et al. Renal tumors. In:  Pizzo PA,  Poplack DG editor. Principles and Practice of Pediatric Oncology. (ed 5). Philadelphia, PA: Lippincott Williams & Wilkins; 2006;p. 905–932
  54. Qualman SJ, Bowen J, Amin MB, et al. Protocol for the examination of specimens from patients with Wilms tumor (nephroblastoma) or other renal tumors of childhood. Arch Pathol Lab Med. 2003;127:1280–1289
  55. Bonadio JF, Storer B, Norkool P, et al. Anaplastic Wilms’ tumor: clinical and pathologic studies. J Clin Oncol. 1985;3:513–520
  56. Green DM, Beckwith JB, Breslow NE, et al. Treatment of children with stages II to IV anaplastic Wilms’ tumor: a report from the National Wilms’ Tumor Study Group. J Clin Oncol. 1994;12:2126–2131
  57. Breslow N, Sharples K, Beckwith JB, et al. Prognostic factors for Wilms’ tumor patients with nonmetastatic disease at diagnosis-results of the third National Wilms’ Tumor Study. Cancer. 1991;68:2345–2353
  58. Pritchard-Jones K, Kelsey A, Vujanic G, et al. Wilm’s Tumor Working Group Older age is an adverse prognostic factor in stage I, favorable histology Wilms’ tumor treated with vincristine monochemotherapy: a study by the United Kingdom Children’s Cancer Study Group. J Clin Oncol. 2003;21:3269–3275
  59. Weirich A, Leuschner I, Harms D, et al. Clinical impact of histologic subtypes in localized non-anaplastic nephroblastoma treated according to the trial and study SIOP-9/GPOH. Ann Oncol. 2001;12:311–319
  60. Grundy PE, Telzerow PE, Breslow N, et al. Loss of heterozygosity for chromosomes 16q and 1p in Wilms’ tumors predicts an adverse outcome. Cancer Res. 1994;54:2331–2333
  61. Grundy RG, Pritchard J, Scambler P, et al. Loss of heterozygosity on chromosome 16 in sporadic Wilms’ tumour. Br J Cancer. 1998;78:1181–1187
  62. Hing S, Lu YJ, Summersgill B, et al. Gain of 1q is associated with adverse outcome in favorable histology Wilms’ tumors. Am J Pathol. 2001;158:393–398
  63. Dome JS, Chung S, Bergemann T, et al. High telomerase reverse transcriptase (hTERT) messenger RNA level correlates with tumor recurrence in patients with favorable histology Wilms’ tumor. Cancer Res. 1999;59:4301–4307
  64. Dome JS, Bockhold CA, Li SM, et al. Telomerase RNA expression as a prognostic marker in patients with favorable histology Wilms tumor. Proc Am Soc Clin Oncol. 2004;23:799;(Abstract)
  65. Beckwith JB, Kiviat NB, Bonadio JF. Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms’ tumor. Pediatr Pathol. 1990;10:1–36
  66. Lowe LH, Isuani BH, Heller RM, et al. Pediatric renal masses: Wilms tumor and beyond. Radiographics. 2000;20:1585–1603
  67. Gylys-Morin V, Hoffer FA, Kozakewich H, et al. Wilms tumor and nephroblastomatosis: imaging characteristics at gadolinium-enhanced MR imaging. Radiology. 1993;188:517–521
  68. White KS, Kirks DR, Bove KE. Imaging of nephroblastomatosis: an overview. Radiology. 1992;182:1–5
  69. Antall PM, Myers MT, Dahms B, et al. Growth of a new intrarenal lesion in the remaining kidney of a patient with bilateral nephroblastomatosis and a previous nephrectomy for Wilms tumor. Med Pediatr Oncol. 2000;35:66–72
  70. Rohrschneider WK, Weirich A, Rieden K, et al. US, CT and MR imaging characteristics of nephroblastomatosis. Pediatr Radiol. 1998;28:435–443

PII: S0037-198X(07)00065-X

doi: 10.1053/j.ro.2007.08.007

Seminars in Roentgenology
Volume 43, Issue 1 , Pages 50-59 , January 2008

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